ea0006oc10 | Reproduction | SFE2003
Sales K
, Gallagher R
, Maudsley S
, Jabbour H
Prostaglandin (PG) E2 has been implicated in benign and neoplastic endometrial pathologies. PGE2 exerts its function by coupling to 4 subtypes of G protein coupled receptors (EP1-EP4). Recently a role for the EP2 receptor in angiogenesis has been established. This study investigated signal transduction and vascular endothelial growth factor (VEGF) expression by the EP2 receptor in Ishikawa endometrial epithelial cells. Ishikawa cells were stably transfect...